COL16A1

Across TCGA cell cohorts, COL16A1 mutation is significantly associated with the mutation status of many other genes, with 6,130 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL16A1-associated genes across cancer lineages are CHD7, DIP2C, and CFAP65. Each is linked with COL16A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COL16A1-to-partner and partner-to-COL16A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHD7 grouped by COL16A1-low versus COL16A1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL16A1→partner) and Y-score (partner→COL16A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CHD7 →	+3.532	+5.247	<.001	<.001	1	8
OVARY	DIP2C →	+2.882	+2.882	.005	.005	1	7
SKIN	CFAP65 →	+2.362	+2.943	.008	.008	1	7
BREAST	PCDHB12 →	+4.857	+4.297	.009	.009	1	6
BLOOD_Lymphoma	SNAP91 →	+4.584	+4.584	.007	.007	1	6
BLOOD_Lymphoma	MYH8 →	+3.362	+4.754	.002	.002	1	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,130 associations by consensus.

CHD7 by COL16A1 expression — SKIN

Explore this box plot interactively →