Across TCGA patient cohorts, COL15A1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,726 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL15A1-associated genes across cancer lineages are GYPC, MEDAG, and PTGIS. Each is linked with COL15A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL15A1-to-partner and partner-to-COL15A1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL15A1→partner) and Y-score (partner→COL15A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GYPC →	+0.942	+0.557	<.001	.003	3	10
HNSC	MEDAG →	+1.555	+0.708	<.001	<.001	3	9
UCEC	PTGIS →	+1.719	+0.698	<.001	<.001	3	9
GBM	CD93 →	+1.114	+0.716	<.001	<.001	3	9
UCEC	RHOJ →	+0.934	+0.603	<.001	<.001	3	9
OV	AOC3 →	+1.580	+0.691	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,726 associations by consensus.

Exploration

COL15A1 survival (RNA) · tumor vs normal (RNA) · all COL15A1 data types