Across TCGA cell cohorts, COL15A1 mutation is significantly associated with the RNA expression of many other genes, with 595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COL15A1-associated genes across cancer lineages are S100A4, CPXCR1, and GOT2. Each is linked with COL15A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL15A1-to-partner and partner-to-COL15A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL15A1→partner) and Y-score (partner→COL15A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	S100A4 →	-1.969	-3.169	.008	.009	3	3
STOMACH	CPXCR1 →	+0.256	+3.584	.003	.009	3	2
SKIN	GOT2 →	+0.503	+2.502	<.001	.005	3	2
SKIN	INIP →	+0.422	+3.169	.004	.009	3	2
BLOOD_Leukemia	SLC25A46 →	+0.617	+3.351	<.001	.003	3	2
SKIN	ZNF519 →	+0.627	+2.588	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 595 associations by consensus.

Exploration

COL15A1 survival (RNA) · tumor vs normal (RNA) · all COL15A1 data types