Across TCGA patient cohorts, COL14A1 mutation is significantly associated with the total protein of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL14A1-associated genes across cancer lineages are Cyclin-B1, FoxM1, and PREX1. Each is linked with COL14A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL14A1-to-partner and partner-to-COL14A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL14A1→partner) and Y-score (partner→COL14A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.618	+1.544	<.001	<.001	3	6
LUSC	FoxM1 →	+0.343	+3.000	.014	.035	2	4
LUSC	PREX1 →	-0.228	-3.160	.017	.019	3	3
LUSC	eEF2K →	+0.410	+3.000	.015	.035	3	3
LUAD	4E-BP1 →	+0.278	+3.087	.014	<.001	3	3
STAD	Bcl-2 →	-0.231	-2.584	.013	.010	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

COL14A1 survival (RNA) · tumor vs normal (RNA) · all COL14A1 data types