Across TCGA cell cohorts, COL14A1 mutation is significantly associated with the RNA expression of many other genes, with 989 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COL14A1-associated genes across cancer lineages are SOHLH1, SPATA16, and EIF3L. Each is linked with COL14A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COL14A1-to-partner and partner-to-COL14A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL14A1→partner) and Y-score (partner→COL14A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	SOHLH1 →	+0.049	+3.807	<.001	.005	3	2
BLOOD_Lymphoma	SPATA16 →	+0.143	+3.058	<.001	.002	3	2
LARGE_INTESTINE	EIF3L →	+0.515	+3.409	<.001	<.001	3	2
LARGE_INTESTINE	HMGXB4 →	+0.535	+2.850	.001	<.001	3	2
LARGE_INTESTINE	IFT27 →	+0.713	+2.244	.003	.003	3	2
LARGE_INTESTINE	GNPNAT1 →	+0.765	+2.936	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 989 associations by consensus.

Exploration

COL14A1 survival (RNA) · tumor vs normal (RNA) · all COL14A1 data types