Across TCGA pan-cancer cohorts, COL13A1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated COL13A1 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher COL13A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated COL13A1 expression acts as an unfavorable survival marker.

HNSC, ESCA, and BLCA are the cancer types where COL13A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	II,III,IV	0.098	0.744	<.001	42	view →
ESCA	DFS	Median	II,III,IV	0.159	0.525	.008	30	view →
BLCA	DFS	Median	All	0.193	0.634	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: COL13A1 tumor-vs-normal RNA expression · all COL13A1 data types