Across TCGA pan-cancer cohorts, COL13A1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated COL13A1 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher COL13A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated COL13A1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD and LSCC are the cancer types where COL13A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	0.795	1.000	.019	10	view →
LSCC	OS	Median	All	0.970	0.763	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: COL13A1 tumor-vs-normal RNA expression · all COL13A1 data types