COL13A1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL13A1 mutation is significantly associated with the RNA expression of many other genes, with 3,906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL13A1-associated genes across cancer lineages are RNASEH1, C8orf33, and GDAP2. Each is linked with COL13A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both COL13A1-to-partner and partner-to-COL13A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL13A1→partner) and Y-score (partner→COL13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNASEH1 →+0.415+1.658.001.00333
SKCMC8orf33 →+0.406+2.434.006.00133
SKCMGDAP2 →+0.381+1.671.003.00333
UCECMETTL2A →+0.508+2.010<.001<.00133
UCECKIF4A →+0.700+2.321<.001<.00133
UCECGCC1 →+0.416+3.491.001.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,906 associations by consensus.

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