COL13A1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL13A1 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COL13A1-associated genes across cancer lineages are C-Raf, Cyclin-E2, and VHL. Each is linked with COL13A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both COL13A1-to-partner and partner-to-COL13A1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL13A1→partner) and Y-score (partner→COL13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC-Raf →+0.130+1.700.018.04234
LUSCCyclin-E2 →+0.134+3.009.044.01933
UCECVHL →-1.166-3.807<.001<.00133
UCECCaspase-7-cleavedD198 →+0.918+3.584<.001.00233
UCECSTAT3_pY705 →-0.444-2.222<.001.00932
SKCMStathmin →+0.173+1.584.013.03532
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Exploration