COL12A1

Across TCGA patient cohorts, COL12A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,721 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COL12A1-associated proteins across cancer lineages are SEC23A, SERPINH1, and MMP14. Each is linked with COL12A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL12A1-to-partner and partner-to-COL12A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL12A1 versus SEC23A in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COL12A1→partner) and Y-score (partner→COL12A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC23A →	+0.303	+1.171	<.001	<.001	3	10
LSCC	SERPINH1 →	+0.544	+1.788	<.001	<.001	3	10
LSCC	MMP14 →	+0.553	+1.294	<.001	<.001	3	9
CCRCC	MXRA5 →	+1.035	+1.284	<.001	<.001	3	9
BRCA	P3H1 →	+0.634	+1.513	<.001	<.001	3	9
HNSC	P3H3 →	+0.743	+1.049	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,721 associations by consensus.

COL12A1 vs SEC23A — BRCA

Explore this scatter interactively →