COL12A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COL12A1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,209 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COL12A1-associated genes across cancer lineages are MYL9, SPARC, and COL5A1. Each is linked with COL12A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both COL12A1-to-partner and partner-to-COL12A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL12A1 versus MYL9 in HNSC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL12A1→partner) and Y-score (partner→COL12A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMYL9 →+1.195+0.526<.001.005310
OVSPARC →+1.833+1.213<.001<.001310
HNSCCOL5A1 →+1.785+0.771<.001<.001310
COADCOL6A1 →+1.577+0.635<.001.001310
OVADAM12 →+1.795+1.189<.001<.001310
COADMXRA5 →+1.810+0.762<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,209 associations by consensus.

COL12A1 vs MYL9 — HNSC

Per-sample scatter of COL12A1 vs MYL9 in HNSC (Pearson r = 0.35).

Explore this scatter interactively →

Exploration