COL11A1

Across TCGA pan-cancer cohorts, COL11A1 Mutation is linked to patient survival in 10 of 34 cancer types, making it a survival-associated COL11A1 data layer compared with 27 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher COL11A1 Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated COL11A1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

UCEC, BLCA, and READ are the cancer types where COL11A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	III,IV	0.813	0.509	.015	20	view →
BLCA	DFS	Median	III,IV	0.851	0.526	.004	16	view →
READ	DFS	Median	All	0.144	0.596	.008	13	view →
PRAD	DFS	Median	All	0.629	0.892	<.001	10	view →
SARC	OS	Median	All	0.085	0.827	<.001	6	view →
OV	OS	Median	All	0.436	0.692	.016	4	view →
ESCA	OS	Median	II,III,IV	0.916	0.649	.031	4	view →
COAD	OS	Median	IV	0.140	0.657	.035	3	view →
LIHC	OS	Median	All	0.105	0.774	.002	3	view →
LUSC	OS	Median	All	0.562	0.386	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

COL11A1–UCEC (DFS)

Open the UCEC breakdown →