COL11A1

Across TCGA pan-cancer cohorts, COL11A1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated COL11A1 data layer compared with 27 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher COL11A1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated COL11A1 expression acts as an unfavorable survival marker.

PDAC, LSCC, and COAD are the cancer types where COL11A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.371	0.942	<.001	63	view →
LSCC	OS	Quartile	All	0.660	0.965	<.001	36	view →
COAD	DFS	Quartile	III,IV	0.728	1.000	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

COL11A1–PDAC (DFS)

Open the PDAC breakdown →