COL10A1

Across TCGA patient cohorts, COL10A1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,175 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COL10A1-associated genes across cancer lineages are MXRA8, COL8A2, and TIMP3. Each is linked with COL10A1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COL10A1-to-partner and partner-to-COL10A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COL10A1 versus MXRA8 in OV, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COL10A1→partner) and Y-score (partner→COL10A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MXRA8 →	+1.206	+0.808	<.001	<.001	3	6
COAD	COL8A2 →	+1.632	+1.578	<.001	<.001	3	6
OV	TIMP3 →	+1.476	+1.269	<.001	<.001	3	5
BRCA	ISM1 →	+1.116	+0.786	.001	<.001	3	5
COAD	COMP →	+3.172	+1.670	<.001	<.001	3	5
OV	AEBP1 →	+1.529	+0.968	.005	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,175 associations by consensus.

COL10A1 vs MXRA8 — OV

Explore this scatter interactively →