COILP1

Across TCGA pan-cancer cohorts, COILP1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of COILP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where COILP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types COILP1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

KIRC, THCA, and BLCA are the cancer types where COILP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in COILP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.115	<.001	11	view →
THCA	All	All	−0.110	<.001	6	view →
BLCA	All	III,IV	+0.120	.001	5	view →
BRCA	All	All	+0.086	.016	4	view →
KIRP	All	All	+0.101	.002	2	view →
LIHC	Male	All	+0.065	<.001	2	view →
HNSC	All	All	+0.050	.024	2	view →
KICH	All	All	−0.075	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

COILP1–KIRC

Open the KIRC breakdown →