Across TCGA patient cohorts, COG8 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,378 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COG8-associated proteins across cancer lineages are DHX38, FTO, and TERF2. Each is linked with COG8 in more than 6 cancer types. Because this analysis shows association rather than direction, both COG8-to-partner and partner-to-COG8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COG8→partner) and Y-score (partner→COG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX38 →	+0.295	+0.482	<.001	<.001	3	7
GBM	FTO →	+0.367	+0.347	<.001	<.001	3	7
GBM	TERF2 →	+0.469	+0.394	<.001	<.001	3	7
GBM	EDC4 →	+0.279	+0.447	<.001	<.001	3	6
GBM	TERF2IP →	+0.362	+0.410	<.001	<.001	3	6
OV	CFDP1 →	+0.537	+0.495	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,378 associations by consensus.

Exploration

COG8 survival (RNA) · tumor vs normal (RNA) · all COG8 data types