Across TCGA patient cohorts, COG8 protein abundance is significantly associated with the RNA expression of many other genes, with 11,782 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COG8-associated genes across cancer lineages are CEP78, GAREM2, and TTC7B. Each is linked with COG8 in more than 4 cancer types. Because this analysis shows association rather than direction, both COG8-to-partner and partner-to-COG8 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COG8→partner) and Y-score (partner→COG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CEP78 →	-0.562	-0.254	.002	<.001	3	5
GBM	GAREM2 →	-0.913	-0.251	.003	.001	3	5
LUAD	TTC7B →	-0.472	-0.228	<.001	<.001	3	5
UCEC	YPEL4 →	-0.997	-0.314	<.001	<.001	3	5
BRCA	RAD54L →	-0.969	-0.255	<.001	<.001	3	5
BRCA	VRK1 →	-0.620	-0.312	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,782 associations by consensus.

Exploration

COG8 survival (RNA) · tumor vs normal (RNA) · all COG8 data types