COG6

Across TCGA patient cohorts, COG6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,731 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COG6-associated genes across cancer lineages are COG3, KDELR3, and DNAJC3. Each is linked with COG6 in more than 5 cancer types. Because this analysis shows association rather than direction, both COG6-to-partner and partner-to-COG6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COG6 versus COG3 in BRCA, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COG6→partner) and Y-score (partner→COG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COG3 →	+0.507	+0.322	<.001	<.001	3	6
OV	KDELR3 →	+1.251	+0.326	<.001	<.001	3	5
BRCA	DNAJC3 →	+0.735	+0.319	<.001	<.001	3	5
UCEC	BLVRA →	+0.783	+0.175	.001	.004	3	5
BRCA	UFM1 →	+0.496	+0.203	<.001	.003	3	5
BRCA	NHLRC3 →	+0.577	+0.183	<.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,731 associations by consensus.

COG6 vs COG3 — BRCA

Explore this scatter interactively →