COG3

Across TCGA cell cohorts, COG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,155 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COG3-associated GO terms across cancer lineages are Retrograde transport, vesicle recycling within Golgi, Intra-Golgi vesicle-mediated transport, and Protein polyufmylation. Each is linked with COG3 in more than 18 cancer types. Because this analysis shows association rather than direction, both COG3-to-partner and partner-to-COG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, vesicle recycling within Golgi grouped by COG3-low versus COG3-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COG3→partner) and Y-score (partner→COG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Retrograde transport, vesicle recycling within Golgi →	+0.154	+0.783	<.001	.001	3	19
LUNG_NSCLC_LUSC	Intra-Golgi vesicle-mediated transport →	+0.105	+0.802	<.001	<.001	3	18
URINARY_TRACT	Protein polyufmylation →	+0.152	+0.801	.003	.003	3	15
URINARY_TRACT	Protein K69-linked ufmylation →	+0.152	+0.801	.003	.003	3	15
OESOPHAGUS	Protein deglycosylation →	+0.116	+0.717	.008	.004	2	15
PANCREAS	Protein demannosylation →	+0.107	+0.687	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,155 associations by consensus.

Retrograde transport, vesicle recycling within Golgi by COG3 expression — KIDNEY

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