COBLL1

Across TCGA patient cohorts, COBLL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,718 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COBLL1-associated proteins across cancer lineages are COBLL1_S326, COBLL1_S788, and COBLL1_S911. Each is linked with COBLL1 in more than 8 cancer types. Because this analysis shows association rather than direction, both COBLL1-to-partner and partner-to-COBLL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COBLL1 versus COBLL1_S326 in UCEC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COBLL1→partner) and Y-score (partner→COBLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COBLL1_S326 →	+0.882	+0.941	<.001	<.001	3	9
BRCA	COBLL1_S788 →	+0.910	+1.001	<.001	<.001	3	9
BRCA	COBLL1_S911 →	+0.852	+1.111	<.001	<.001	3	8
LSCC	COBLL1_S947 →	+0.816	+0.877	<.001	<.001	3	8
BRCA	COBLL1_S356 →	+0.775	+1.094	.001	.001	3	7
LSCC	COBLL1_S366 →	+0.993	+1.011	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,718 associations by consensus.

COBLL1 vs COBLL1_S326 — UCEC

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