COBLL1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COBLL1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,834 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COBLL1-associated genes across cancer lineages are SNORA70F, HASPIN, and FHL5. Each is linked with COBLL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COBLL1-to-partner and partner-to-COBLL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COBLL1 versus SNORA70F in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COBLL1→partner) and Y-score (partner→COBLL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCSNORA70F →+0.915+0.517<.001<.00138
COADHASPIN →-0.753-0.330<.001<.00136
UCECFHL5 →+0.892+0.304<.001.00435
LUADFANCI →-0.655-0.258<.001<.00135
LSCCSLC38A11 →+1.326+0.495<.001<.00135
BRCAFAM110C →+1.658+0.505<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,834 associations by consensus.

COBLL1 vs SNORA70F — LSCC

Per-sample scatter of COBLL1 vs SNORA70F in LSCC (Pearson r = 0.74).

Explore this scatter interactively →

Exploration