COBL

Across TCGA patient cohorts, COBL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,969 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COBL-associated proteins across cancer lineages are COBL_S815, COBL_S235, and COBL_S324. Each is linked with COBL in more than 9 cancer types. Because this analysis shows association rather than direction, both COBL-to-partner and partner-to-COBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COBL versus COBL_S815 in OV, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COBL→partner) and Y-score (partner→COBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COBL_S815 →	+1.373	+1.594	<.001	<.001	3	10
OV	COBL_S235 →	+1.564	+1.025	<.001	<.001	3	9
HNSC	COBL_S324 →	+1.348	+0.589	<.001	.001	3	9
BRCA	COBL_S440 →	+0.956	+1.045	<.001	<.001	3	9
BRCA	COBL_S284 →	+1.298	+1.020	<.001	<.001	3	8
CCRCC	COBL_S917 →	+1.109	+1.316	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,969 associations by consensus.

COBL vs COBL_S815 — OV

Explore this scatter interactively →