COA6

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COA6 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible COA6-associated genes across cancer lineages are CD4+ Tcm. Each is linked with COA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both COA6-to-partner and partner-to-COA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by COA6-low versus COA6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COA6→partner) and Y-score (partner→COA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCCD4+ Tcm →+0.014+6.593<.001.02031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tcm by COA6 expression — LUSC

Box plot of CD4+ Tcm in COA6-low vs COA6-high samples in LUSC.

Explore this box plot interactively →

Exploration