COA6-AS1

Across TCGA pan-cancer cohorts, COA6-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated COA6-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher COA6-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated COA6-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and PAAD show a favorable association.

KIRC, BLCA, and ACC are the cancer types where COA6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.457	0.697	<.001	147	view →
BLCA	DFS	Quartile	All	0.622	0.423	<.001	68	view →
ACC	OS	Tertile	All	0.444	1.000	.001	56	view →
PAAD	OS	Median	All	0.513	0.219	<.001	47	view →
LUSC	OS	Median	All	0.834	0.713	<.001	35	view →
ESCA	DFS	Median	All	1.000	0.481	.003	18	view →
UVM	DFS	Median	All	0.719	0.485	.012	18	view →
LUAD	DFS	Quartile	IV	0.528	1.000	.028	14	view →
STAD	OS	Quartile	IV	0.855	0.403	.024	11	view →
READ	DFS	Median	III,IV	0.442	0.635	.038	9	view →
UCEC	DFS	Median	IV	0.698	0.267	.017	8	view →
LIHC	OS	Tertile	All	0.717	0.852	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

COA6-AS1–KIRC (DFS)

Open the KIRC breakdown →