Across TCGA patient cohorts, COA5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,892 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COA5-associated proteins across cancer lineages are TSN, ZNF638, and GTF3C4. Each is linked with COA5 in more than 6 cancer types. Because this analysis shows association rather than direction, both COA5-to-partner and partner-to-COA5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COA5→partner) and Y-score (partner→COA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSN →	+0.330	+0.307	<.001	<.001	2	7
LSCC	ZNF638 →	+0.239	+0.489	<.001	<.001	3	6
HNSC	GTF3C4 →	+0.311	+0.832	<.001	<.001	3	6
OV	IRF2BP2_S175 →	+0.637	+0.639	<.001	<.001	3	6
LSCC	MYEF2 →	+0.806	+0.331	<.001	<.001	3	6
LSCC	S100A9_T113 →	-1.077	-0.477	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,892 associations by consensus.

Exploration

COA5 survival (RNA) · tumor vs normal (RNA) · all COA5 data types