CNTNAP4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNTNAP4 protein abundance is significantly associated with the RNA expression of many other genes, with 637 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNTNAP4-associated genes across cancer lineages are NEFH, CBX7, and CACNA1I. Each is linked with CNTNAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTNAP4-to-partner and partner-to-CNTNAP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTNAP4 versus NEFH in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP4→partner) and Y-score (partner→CNTNAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNEFH →+0.947+0.743.003<.00131
GBMCBX7 →+0.654+0.611.001.00231
GBMCACNA1I →+0.523+0.626.002.00231
GBMKIAA0930 →+0.604+0.664<.001<.00131
GBMPSMC1 →-0.332-0.770<.001.00231
GBMPPP4R3A →-0.337-0.759.002<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 637 associations by consensus.

CNTNAP4 vs NEFH — GBM

Per-sample scatter of CNTNAP4 vs NEFH in GBM (Pearson r = 0.34).

Explore this scatter interactively →

Exploration