CNTNAP4

Across TCGA cell cohorts, CNTNAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 622 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNTNAP4-associated GO terms across cancer lineages are Regulation of synaptic transmission, dopaminergic, Response to histamine, and Mitochondrion organization. Each is linked with CNTNAP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTNAP4-to-partner and partner-to-CNTNAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of synaptic transmission, dopaminergic grouped by CNTNAP4-low versus CNTNAP4-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP4→partner) and Y-score (partner→CNTNAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of synaptic transmission, dopaminergic →	-0.229	-0.552	<.001	.002	3	5
BLOOD_Leukemia	Response to histamine →	-0.128	-0.988	<.001	.003	3	3
LUNG_SCLC	Mitochondrion organization →	+0.059	+0.609	.005	.007	1	5
KIDNEY	Regulation of enamel mineralization →	-0.272	-0.008	<.001	.007	3	3
BLOOD_Leukemia	Negative regulation of phospholipase C/protein kinase C signal transduction →	-0.162	-0.854	<.001	.001	3	3
BLOOD_Leukemia	Acylglycerol transport →	+0.646	+0.734	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 622 associations by consensus.

Regulation of synaptic transmission, dopaminergic by CNTNAP4 expression — SKIN

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