CNTNAP4

Across TCGA cell cohorts, CNTNAP4 mutation is significantly associated with the RNA expression of many other genes, with 707 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTNAP4-associated genes across cancer lineages are RIOK1, TEX55, and MED26. Each is linked with CNTNAP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNTNAP4-to-partner and partner-to-CNTNAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RIOK1 grouped by CNTNAP4-low versus CNTNAP4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP4→partner) and Y-score (partner→CNTNAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RIOK1 →	+0.521	+3.169	.006	.006	3	3
BREAST	TEX55 →	+0.036	+4.199	<.001	.007	3	2
LARGE_INTESTINE	MED26 →	+0.272	+3.067	.005	.009	3	2
LARGE_INTESTINE	KAT2A →	+0.524	+2.628	<.001	.002	3	2
LARGE_INTESTINE	UBE2G1 →	+0.517	+3.169	.005	.006	3	2
LARGE_INTESTINE	TMEM237 →	+0.726	+2.628	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 707 associations by consensus.

RIOK1 by CNTNAP4 expression — LARGE_INTESTINE

Explore this box plot interactively →