CNTNAP2

Across TCGA patient cohorts, CNTNAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,700 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNTNAP2-associated genes across cancer lineages are SLC1A4, KCNMA1, and CHST1. Each is linked with CNTNAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTNAP2-to-partner and partner-to-CNTNAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTNAP2 versus SLC1A4 in BRCA, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP2→partner) and Y-score (partner→CNTNAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC1A4 →	+1.862	+2.045	.003	.005	3	2
BRCA	KCNMA1 →	+2.203	+2.918	<.001	.005	3	2
BRCA	CHST1 →	+2.278	+1.775	.001	.003	3	2
BRCA	AKAP5 →	+1.557	+2.337	.007	.002	3	2
BRCA	C9orf129 →	+1.162	+2.440	.009	.001	3	2
BRCA	LINC01587 →	-0.732	-2.468	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,700 associations by consensus.

CNTNAP2 vs SLC1A4 — BRCA

Explore this scatter interactively →