CNTNAP1

Across TCGA cell cohorts, CNTNAP1 mutation is significantly associated with the RNA expression of many other genes, with 393 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTNAP1-associated genes across cancer lineages are ABCC12, LYG1, and OR4D6. Each is linked with CNTNAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTNAP1-to-partner and partner-to-CNTNAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCC12 grouped by CNTNAP1-low versus CNTNAP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTNAP1→partner) and Y-score (partner→CNTNAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ABCC12 →	+0.059	+3.736	<.001	.009	3	2
LARGE_INTESTINE	LYG1 →	+0.920	+3.212	.001	.006	3	2
SOFT_TISSUE	OR4D6 →	+0.028	+4.392	<.001	.004	3	1
SOFT_TISSUE	SOX14 →	+0.736	+3.882	<.001	.004	3	1
SOFT_TISSUE	SLC22A25 →	+0.017	+3.882	<.001	.004	3	1
BLOOD_Lymphoma	GFRA4 →	+0.008	+3.714	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 393 associations by consensus.

ABCC12 by CNTNAP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →