CNTN6

Across TCGA patient cohorts, CNTN6 mutation is significantly associated with the total protein of many other genes, with 65 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTN6-associated genes across cancer lineages are TFRC, ATM, and Caspase-7-cleavedD198. Each is linked with CNTN6 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTN6-to-partner and partner-to-CNTN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CNTN6-low versus CNTN6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN6→partner) and Y-score (partner→CNTN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	TFRC →	+0.740	+1.916	.002	.009	3	5
UCEC	ATM →	-0.510	-1.754	<.001	<.001	3	5
BRCA	Caspase-7-cleavedD198 →	+1.005	+3.169	<.001	.020	3	4
UCEC	STAT3_pY705 →	-0.352	-2.000	<.001	<.001	3	4
STAD	FoxM1 →	+0.281	+1.905	.004	.027	3	3
STAD	PR →	-0.123	-1.786	.013	.025	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

TFRC by CNTN6 expression — LUSC

Explore this box plot interactively →