CNTN6

Across TCGA cell cohorts, CNTN6 mutation is significantly associated with the RNA expression of many other genes, with 804 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN6-associated genes across cancer lineages are PPCS, PICK1, and MANBA. Each is linked with CNTN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTN6-to-partner and partner-to-CNTN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPCS grouped by CNTN6-low versus CNTN6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN6→partner) and Y-score (partner→CNTN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PPCS →	+0.391	+3.502	.003	.001	3	2
LARGE_INTESTINE	PICK1 →	+0.531	+3.169	.006	.006	3	2
LARGE_INTESTINE	MANBA →	+0.693	+1.850	<.001	.006	3	2
LARGE_INTESTINE	KLHL2 →	+0.578	+2.364	.002	<.001	3	2
LARGE_INTESTINE	USP4 →	+0.431	+3.321	.003	.002	3	2
LARGE_INTESTINE	DDX59 →	+0.419	+1.936	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 804 associations by consensus.

PPCS by CNTN6 expression — SKIN

Explore this box plot interactively →