CNTN5

Across TCGA cell cohorts, CNTN5 mutation is significantly associated with the RNA expression of many other genes, with 602 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN5-associated genes across cancer lineages are FDXACB1, TNFRSF10A, and SMIM8. Each is linked with CNTN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNTN5-to-partner and partner-to-CNTN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FDXACB1 grouped by CNTN5-low versus CNTN5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN5→partner) and Y-score (partner→CNTN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FDXACB1 →	+0.464	+2.584	.001	.002	3	3
SKIN	TNFRSF10A →	+1.046	+2.043	.008	.008	3	2
SKIN	SMIM8 →	+0.393	+2.459	<.001	.006	3	2
SKIN	RGS3 →	+1.355	+2.743	<.001	.001	3	2
LARGE_INTESTINE	ZFAND4 →	+0.733	+1.807	<.001	.005	3	2
SKIN	HES7 →	+0.375	+2.043	.003	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 602 associations by consensus.

FDXACB1 by CNTN5 expression — LARGE_INTESTINE

Explore this box plot interactively →