CNTN3

Across TCGA patient cohorts, CNTN3 mutation is significantly associated with the RNA expression of many other genes, with 4,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTN3-associated genes across cancer lineages are CENPA, UBE2SP1, and UBE2S. Each is linked with CNTN3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTN3-to-partner and partner-to-CNTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPA grouped by CNTN3-low versus CNTN3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN3→partner) and Y-score (partner→CNTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CENPA →	+0.984	+2.999	<.001	<.001	3	5
SKCM	UBE2SP1 →	+0.460	+2.434	.004	.001	3	5
SKCM	UBE2S →	+0.501	+1.735	.001	.002	3	5
ACC	RNU6-579P →	+0.825	+4.887	<.001	.009	3	4
LUAD	CDKN3 →	+0.682	+1.847	.008	.008	3	4
LUAD	PKMYT1 →	+0.650	+1.847	.003	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,937 associations by consensus.

CENPA by CNTN3 expression — LUAD

Explore this box plot interactively →