CNTN3

Across TCGA cell cohorts, CNTN3 mutation is significantly associated with the RNA expression of many other genes, with 378 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN3-associated genes across cancer lineages are KLRC3, ENOSF1, and CTU1. Each is linked with CNTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTN3-to-partner and partner-to-CNTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLRC3 grouped by CNTN3-low versus CNTN3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN3→partner) and Y-score (partner→CNTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KLRC3 →	+0.035	+3.906	.001	.009	3	2
LUNG_NSCLC_LUSC	ENOSF1 →	+0.842	+3.106	.003	.004	3	2
LUNG_NSCLC_LUSC	CTU1 →	+0.587	+3.106	.001	.004	3	2
LARGE_INTESTINE	MIB2 →	+1.170	+2.628	<.001	.002	3	2
CNS	STH →	+0.117	+2.523	<.001	.007	3	2
LARGE_INTESTINE	MTARC2 →	+1.197	+3.743	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 378 associations by consensus.

KLRC3 by CNTN3 expression — BLOOD_Myeloma

Explore this box plot interactively →