Across TCGA patient cohorts, CNTN2 mutation is significantly associated with the RNA expression of many other genes, with 4,910 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTN2-associated genes across cancer lineages are LRRC59, HARS1, and AURKB. Each is linked with CNTN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNTN2-to-partner and partner-to-CNTN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN2→partner) and Y-score (partner→CNTN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRRC59 →	+0.472	+2.435	<.001	<.001	3	4
COAD	HARS1 →	+0.277	+2.713	.002	.003	3	4
UCEC	AURKB →	+0.639	+2.673	<.001	<.001	3	4
UCEC	CDT1 →	+0.791	+2.394	<.001	<.001	3	4
UCEC	MAP6D1 →	+0.360	+1.836	.003	.001	3	4
UCEC	PSMD9 →	+0.325	+1.369	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,910 associations by consensus.

Exploration

CNTN2 survival (RNA) · tumor vs normal (RNA) · all CNTN2 data types