CNTN1

Across TCGA patient cohorts, CNTN1 mutation is significantly associated with the total protein of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNTN1-associated genes across cancer lineages are JNK_pT183_Y185, Src_pY416, and Src_pY527. Each is linked with CNTN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNTN1-to-partner and partner-to-CNTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK_pT183_Y185 grouped by CNTN1-low versus CNTN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN1→partner) and Y-score (partner→CNTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK_pT183_Y185 →	-0.123	-1.716	.009	.003	3	4
UCEC	Src_pY416 →	-0.190	-1.618	.004	<.001	3	3
UCEC	Src_pY527 →	-0.319	-1.864	.008	.002	3	3
COAD	Caspase-7-cleavedD198 →	+0.775	+2.338	.005	.017	3	3
UCEC	4E-BP1 →	+0.252	+1.614	<.001	.010	3	3
UCEC	eEF2K →	+0.207	+1.678	.034	.021	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

JNK_pT183_Y185 by CNTN1 expression — UCEC

Explore this box plot interactively →