CNTN1

Across TCGA cell cohorts, CNTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,170 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible CNTN1-associated GO terms across cancer lineages are Negative regulation of neurotransmitter uptake, Regulation of serotonin uptake, and Negative regulation of serotonin uptake. Each is linked with CNTN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CNTN1-to-partner and partner-to-CNTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of neurotransmitter uptake grouped by CNTN1-low versus CNTN1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN1→partner) and Y-score (partner→CNTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of neurotransmitter uptake →	+1.533	+5.449	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Regulation of serotonin uptake →	+1.501	+4.618	.001	<.001	3	8
LUNG_NSCLC_LUSC	Negative regulation of serotonin uptake →	+1.533	+5.449	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Oligosaccharide biosynthetic process →	-0.111	-2.806	.005	.005	3	7
LUNG_NSCLC_LUSC	Protein oxidation →	-0.773	-3.518	.003	<.001	3	7
LARGE_INTESTINE	Potassium ion transmembrane transport →	-0.032	-1.096	.005	.007	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,170 associations by consensus.

Negative regulation of neurotransmitter uptake by CNTN1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →