CNTN1

Across TCGA cell cohorts, CNTN1 mutation is significantly associated with the RNA expression of many other genes, with 495 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNTN1-associated genes across cancer lineages are CR2, FAM124A, and MRPS18C. Each is linked with CNTN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNTN1-to-partner and partner-to-CNTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CR2 grouped by CNTN1-low versus CNTN1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTN1→partner) and Y-score (partner→CNTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CR2 →	+0.516	+2.451	.009	.009	3	2
LARGE_INTESTINE	FAM124A →	+0.626	+3.465	.001	.002	3	2
LARGE_INTESTINE	MRPS18C →	+0.610	+3.588	<.001	<.001	3	2
LARGE_INTESTINE	F11 →	+0.037	+2.397	<.001	.003	3	2
LUNG_NSCLC_LUAD	CRLF3 →	+0.591	+3.206	<.001	.006	3	2
OVARY	FXYD4 →	+0.723	+3.662	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 495 associations by consensus.

CR2 by CNTN1 expression — LARGE_INTESTINE

Explore this box plot interactively →