CNTFR

Across TCGA cell cohorts, CNTFR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,624 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CNTFR-associated GO terms across cancer lineages are Ribonucleoside triphosphate biosynthetic process, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with CNTFR in more than 10 cancer types. Because this analysis shows association rather than direction, both CNTFR-to-partner and partner-to-CNTFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribonucleoside triphosphate biosynthetic process grouped by CNTFR-low versus CNTFR-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTFR→partner) and Y-score (partner→CNTFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Ribonucleoside triphosphate biosynthetic process →	+0.108	+2.420	<.001	<.001	3	11
SKIN	Purine nucleoside triphosphate biosynthetic process →	+0.101	+0.650	<.001	.001	3	11
SKIN	Purine ribonucleoside triphosphate biosynthetic process →	+0.101	+0.650	<.001	.001	3	11
BONE	Protein-DNA complex organization →	+0.088	+1.737	<.001	<.001	3	11
BONE	Positive regulation of sodium ion transport →	-0.186	-1.886	<.001	<.001	3	10
BONE	DNA-templated transcription initiation →	+0.079	+1.891	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,624 associations by consensus.

Ribonucleoside triphosphate biosynthetic process by CNTFR expression — LUNG_SCLC

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