CNTFR

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNTFR protein abundance is significantly associated with the RNA expression of many other genes, with 2,476 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNTFR-associated genes across cancer lineages are TYMP, FOSL2, and ZNF620. Each is linked with CNTFR in more than 4 cancer types. Because this analysis shows association rather than direction, both CNTFR-to-partner and partner-to-CNTFR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNTFR versus TYMP in BLOOD_Lymphoma, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTFR→partner) and Y-score (partner→CNTFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTYMP →+3.252+3.571<.001<.00135
URINARY_TRACTFOSL2 →+1.042+2.878.005.00134
BLOOD_LeukemiaZNF620 →-1.346-2.641<.001.00134
KIDNEYRAB11B →-0.906-1.776.004.00234
BONEAKR1B1 →+1.881+1.840.005.00434
LUNG_NSCLC_LUADOR11H7 →-0.256-1.493.002.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,476 associations by consensus.

CNTFR vs TYMP — BLOOD_Lymphoma

Per-sample scatter of CNTFR vs TYMP in BLOOD_Lymphoma (Pearson r = 0.89).

Explore this scatter interactively →

Exploration