CNTFR

Across TCGA cell cohorts, CNTFR protein abundance is significantly associated with the go_rna of many other GO terms, with 1,716 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNTFR-associated GO terms across cancer lineages are rRNA 3'-end processing, Negative regulation of leukocyte cell-cell adhesion, and Nucleosome disassembly. Each is linked with CNTFR in more than 5 cancer types. Because this analysis shows association rather than direction, both CNTFR-to-partner and partner-to-CNTFR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA 3'-end processing grouped by CNTFR-low versus CNTFR-high in UPPER_AERODIGESTIVE_TRACT.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNTFR→partner) and Y-score (partner→CNTFR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	rRNA 3'-end processing →	-0.109	-1.966	<.001	.001	3	6
BONE	Negative regulation of leukocyte cell-cell adhesion →	+0.069	+1.840	.002	.004	3	5
LUNG_NSCLC_LUAD	Nucleosome disassembly →	-0.076	-1.750	.004	.002	3	5
BLOOD_Lymphoma	Pyrimidine nucleoside monophosphate catabolic process →	+0.265	+3.676	<.001	<.001	3	5
BLOOD_Lymphoma	Pyrimidine deoxyribonucleoside monophosphate catabolic process →	+0.265	+3.676	<.001	<.001	3	5
BONE	Negative regulation of leukocyte activation →	+0.056	+1.840	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

rRNA 3'-end processing by CNTFR expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →