CNRIP1

Across TCGA pan-cancer cohorts, CNRIP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CNRIP1 data layer compared with 22 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CNRIP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CNRIP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, UCEC, and PDAC are the cancer types where CNRIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.935	0.757	.002	47	view →
UCEC	OS	Median	II,III,IV	0.620	1.000	.011	32	view →
PDAC	DFS	Median	All	0.826	0.697	.003	16	view →
LUAD	DFS	Tertile	II,III,IV	0.727	0.993	.006	8	view →
COAD	DFS	Median	All	0.904	1.000	.045	6	view →
LSCC	OS	Tertile	All	0.931	1.000	.033	6	view →
GBM	DFS	Tertile	All	0.809	0.658	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CNRIP1–CCRCC (OS)

Open the CCRCC breakdown →