CNRIP1

Across TCGA patient cohorts, CNRIP1 mutation is significantly associated with the RNA expression of many other genes, with 234 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNRIP1-associated genes across cancer lineages are KRT8P6, RNU6-1292P, and RNU6ATAC30P. Each is linked with CNRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNRIP1-to-partner and partner-to-CNRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT8P6 grouped by CNRIP1-low versus CNRIP1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNRIP1→partner) and Y-score (partner→CNRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KRT8P6 →	+0.095	+3.569	.001	.004	3	2
UCEC	RNU6-1292P →	+0.357	+3.716	<.001	.002	3	2
UCEC	RNU6ATAC30P →	+0.508	+2.739	<.001	.001	3	2
UCEC	MTND3P2 →	+0.245	+3.115	<.001	.007	3	2
UCEC	GMFBP1 →	+0.249	+2.426	<.001	.004	3	2
LUSC	GNAT2 →	+0.027	+4.548	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 234 associations by consensus.

KRT8P6 by CNRIP1 expression — COAD

Explore this box plot interactively →