CNRIP1

Across TCGA patient cohorts, CNRIP1 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNRIP1-associated genes across cancer lineages are PRAS40_pT246, Tuberin, and JNK2. Each is linked with CNRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNRIP1-to-partner and partner-to-CNRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAS40_pT246 grouped by CNRIP1-low versus CNRIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNRIP1→partner) and Y-score (partner→CNRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRAS40_pT246 →	+0.185	+2.183	.040	.035	3	1
UCEC	Tuberin →	+0.339	+3.009	.016	.019	3	1
UCEC	JNK2 →	+0.287	+3.321	.005	.010	2	1
UCEC	cIAP →	+0.177	+3.348	.013	.005	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

PRAS40_pT246 by CNRIP1 expression — UCEC

Explore this box plot interactively →