Across TCGA patient cohorts, CNR2 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNR2-associated genes across cancer lineages are CD49b, 4E-BP1, and 14-3-3_beta. Each is linked with CNR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNR2-to-partner and partner-to-CNR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNR2→partner) and Y-score (partner→CNR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD49b →	-0.341	-2.986	.010	.035	3	2
UCEC	4E-BP1 →	+0.299	+2.199	.017	.033	3	2
UCEC	14-3-3_beta →	-0.129	-2.571	.005	.011	3	1
UCEC	Fibronectin →	-0.354	-3.312	.021	.010	3	1
UCEC	Heregulin →	-0.198	-2.584	<.001	.010	3	1
UCEC	MEK1 →	+0.348	+3.169	.041	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

CNR2 survival (RNA) · tumor vs normal (RNA) · all CNR2 data types