CNR2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNR2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CNR2-associated genes across cancer lineages are MYF5, FABP12, and KRTAP22-2. Each is linked with CNR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNR2-to-partner and partner-to-CNR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNR2→partner) and Y-score (partner→CNR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaMYF5 →+0.016+4.807<.001.00631
BLOOD_MyelomaFABP12 →+0.060+4.807<.001.00631
BLOOD_MyelomaKRTAP22-2 →+0.229+4.807<.001.00631
LARGE_INTESTINEMAGEB4 →+0.022+5.415<.001.00431
LARGE_INTESTINERBMY1B →+0.006+5.415<.001.00431
LARGE_INTESTINERBMY1D →+0.006+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

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