Across TCGA cell cohorts, CNR2 mutation is significantly associated with the mutation status of many other genes, with 935 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CNR2-associated genes across cancer lineages are SOGA3, POGZ, and ATXN7L1. Each is linked with CNR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNR2-to-partner and partner-to-CNR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNR2→partner) and Y-score (partner→CNR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SOGA3 →	+4.614	+4.614	.006	.006	1	3
SKIN	POGZ →	+4.638	+4.638	<.001	<.001	1	3
SKIN	ATXN7L1 →	+4.053	+4.357	.001	.001	1	3
CNS	ISL1 →	+5.614	+5.044	.003	.003	1	3
SKIN	KMT2A →	+2.830	+3.548	.009	.009	1	3
CNS	IDE →	+4.614	+4.614	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 935 associations by consensus.

Exploration

CNR2 survival (RNA) · tumor vs normal (RNA) · all CNR2 data types