CNPY2

Across TCGA patient cohorts, CNPY2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,437 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CNPY2-associated genes across cancer lineages are GNL1, PGAP2, and RNF20. Each is linked with CNPY2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CNPY2-to-partner and partner-to-CNPY2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNPY2 versus GNL1 in LSCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPY2→partner) and Y-score (partner→CNPY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GNL1 →	-0.547	-0.270	<.001	<.001	3	4
COAD	PGAP2 →	-0.542	-0.440	<.001	<.001	3	3
LSCC	RNF20 →	-0.412	-0.295	<.001	<.001	3	3
LUAD	DENND5B →	+0.661	+0.332	<.001	<.001	3	3
LSCC	ACTG1P22 →	+0.638	+0.269	<.001	<.001	3	3
OV	GCDH →	-0.518	-0.272	.008	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,437 associations by consensus.

CNPY2 vs GNL1 — LSCC

Explore this scatter interactively →