CNPY2

Across TCGA patient cohorts, CNPY2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNPY2-associated genes across cancer lineages are Fibroblasts, Monocytes, and Macrophages. Each is linked with CNPY2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNPY2-to-partner and partner-to-CNPY2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by CNPY2-low versus CNPY2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNPY2→partner) and Y-score (partner→CNPY2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Fibroblasts →	+0.025	+5.721	.044	.036	3	1
SKCM	Monocytes →	+0.014	+5.225	<.001	.034	3	1
UCEC	Macrophages →	+0.017	+4.176	.045	<.001	3	1
UCEC	Macrophages M2 →	+0.019	+3.118	.001	.016	2	1
UCEC	aDC →	+0.113	+3.010	.008	.020	1	1
UCEC	Th1 cells →	+0.108	+3.000	.046	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Fibroblasts by CNPY2 expression — COAD

Explore this box plot interactively →